Marburg Virus Outbreaks: A Lethal and Complex Threat | Estateplanning

Marburg virus outbreaks have been reported since 1967, with a mortality rate ranging from 23% to 90%, according to the World Health Organization (WHO). The virus is a member of the Filoviridae family, which also includes Ebola, and is primarily transmitted through direct contact with infected bodily fluids. The largest outbreak occurred in Angola in 2005, resulting in 227 deaths out of 252 reported cases, with a staggering 90% mortality rate. Despite its high lethality, Marburg virus research has been relatively understudied compared to Ebola, with only a handful of vaccine candidates in development. The lack of a licensed vaccine or treatment has significant implications for global health security, particularly in regions with limited healthcare infrastructure. As of 2022, the WHO has reported a total of 475 cases and 373 deaths due to Marburg virus outbreaks, with a case fatality rate of 78.5%, highlighting the need for continued research and investment in prevention and control measures.